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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKG
All Species:
11.21
Human Site:
T124
Identified Species:
20.56
UniProt:
P49619
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49619
NP_001074213.1
791
89096
T124
D
E
A
C
A
P
D
T
E
S
N
M
A
E
K
Chimpanzee
Pan troglodytes
XP_001152821
791
89168
T124
D
E
A
C
A
P
D
T
E
S
N
M
A
E
K
Rhesus Macaque
Macaca mulatta
XP_001092912
791
89195
T124
D
E
A
C
A
P
D
T
E
S
N
M
A
E
M
Dog
Lupus familis
XP_545239
790
88986
E124
E
A
C
A
P
D
T
E
S
K
I
T
E
K
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q91WG7
788
88505
K124
C
A
P
D
T
E
S
K
T
T
K
T
Q
A
P
Rat
Rattus norvegicus
P49620
788
88503
K124
C
A
P
D
T
E
S
K
P
I
K
T
Q
V
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511802
697
78726
I85
S
S
E
L
E
N
I
I
S
Q
M
M
H
V
A
Chicken
Gallus gallus
XP_422650
933
102351
P128
A
A
G
P
A
D
G
P
E
R
P
P
P
P
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696120
893
99287
G129
A
P
I
T
G
M
N
G
K
S
I
L
S
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q01583
1211
132942
S128
G
S
I
P
N
I
N
S
I
A
E
L
M
P
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03603
812
91362
S126
Q
T
D
R
S
Q
S
S
E
P
Q
A
L
V
C
Sea Urchin
Strong. purpuratus
XP_001197889
1217
132437
G448
V
V
S
V
S
A
N
G
Q
L
R
L
G
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
H116
V
A
S
E
S
F
F
H
R
C
T
I
C
G
A
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.8
94
N.A.
89.7
88.2
N.A.
51.3
54.9
N.A.
59.2
N.A.
35.5
N.A.
46
38.3
Protein Similarity:
100
99.7
97.8
95.5
N.A.
94.1
93
N.A.
63.5
65.9
N.A.
72.7
N.A.
46.5
N.A.
63.2
48.8
P-Site Identity:
100
100
93.3
0
N.A.
0
0
N.A.
6.6
13.3
N.A.
6.6
N.A.
0
N.A.
6.6
0
P-Site Similarity:
100
100
93.3
20
N.A.
6.6
0
N.A.
6.6
13.3
N.A.
33.3
N.A.
33.3
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
39
24
8
31
8
0
0
0
8
0
8
24
16
16
% A
% Cys:
16
0
8
24
0
0
0
0
0
8
0
0
8
0
8
% C
% Asp:
24
0
8
16
0
16
24
0
0
0
0
0
0
0
0
% D
% Glu:
8
24
8
8
8
16
0
8
39
0
8
0
8
24
0
% E
% Phe:
0
0
0
0
0
8
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
8
0
8
16
0
0
0
0
8
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% H
% Ile:
0
0
16
0
0
8
8
8
8
8
16
8
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
16
8
8
16
0
0
8
16
% K
% Leu:
0
0
0
8
0
0
0
0
0
8
0
24
8
0
0
% L
% Met:
0
0
0
0
0
8
0
0
0
0
8
31
8
0
16
% M
% Asn:
0
0
0
0
8
8
24
0
0
0
24
0
0
0
0
% N
% Pro:
0
8
16
16
8
24
0
8
8
8
8
8
8
16
24
% P
% Gln:
8
0
0
0
0
8
0
0
8
8
8
0
16
0
16
% Q
% Arg:
0
0
0
8
0
0
0
0
8
8
8
0
0
0
0
% R
% Ser:
8
16
16
0
24
0
24
16
16
31
0
0
8
8
0
% S
% Thr:
0
8
0
8
16
0
8
24
8
8
8
24
0
0
8
% T
% Val:
16
8
0
8
0
0
0
0
0
0
0
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _